Knox Van Dyke, PhD

 

Knox Van Dyke, Ph.D., is recognized by Continental Who’s Who as a Pinnacle Professional Member in the fields of Biochemistry and Molecular Pharmacology. Dr. Van Dyke serves as a Professor of Biochemistry and Molecular Pharmacology at West Virginia University Medical Center. His expertise lies in the areas of chronic diseases and he brings over 50 years of field experience to his position. According to its website, the Health Research Department at West Virginia University Medical Center “focuses on structures, processes and transitions that impact the care and quality of life of underserved and medically complex populations.” At the beginning of his academic career, Dr. Van Dyke “completed his Ph.D. in Biochemistry in the Edward A. Doisy – Nobel Prize Department at Saint Louis University in 1966,” according to Omics International. Additionally, he completed “Postdoctoral studies in the Department of Pharmacology at West Virginia University. During this time, he developed the first effective drug screening system for antimalarial drugs while screening over 10,000 drugs,” and discovered Mefloquine, Halofantrine used for Malaria.

The solution for chloroquine resistance was discovered in his lab when it was found that tetrandrine could block ATP dependent exit pumps and it also is a natural calcium channel inhibitor which causes a greater than 40 fold potentiation (increase) in the power of chloroquine which cured Aotus monkeys infected with chloroquine resistant falciparum human malaria (the deadliest form). Tetrandrine has now been found effective against the deadly Ebola virus and it has been shown that its calcium channel inhibition activity which causes part of its effect against malaria is likely responsible for its anti-Ebola activity. Additionally, Dr. Van Dyke “first solved the problem of black lung disease and silicosis by demonstrating that coal dust per se is not particularly toxic to human cells compared to silica and that silica is not particularly toxic alone, but it is contaminated with calcium.” He has patented new drugs which treat and slow similar diseases including asbestosis and radiation toxicity. Dr. Van Dyke has also studied diabetes, types one and two, and “found the actual cause of these diseases originates from a toxic peroxide called peroxynitrite (OON=O-) or its carbon dioxide derivative or similar products “. Currently, none of the present day drugs addresses the real toxicity but mostly focus on controlling sugar or body weight.

Poorly controlled diabetes causes the same inherent toxicity as tightly controlled diabetes. The public is wasting a great deal of their money on treatments that are not fully effective and at a high cost. In addition to his extensive studies and discoveries, Dr. Van Dyke has published seven books on cellular and immunologic aspects of luminescence and disease states as well as numerous articles throughout his career, including well more 300 different publications. He has also developed more than 150 different patents. To further his professional development, Dr. Van Dyke is a continuous member of the American Association of Pharmacology and Experimental Therapeutics, and former member of the New York Academy of Science. He is currently developing new, effective and inexpensive drugs for Alzheimer’s and Parkinson’s disease as well as multiple sclerosis, amyotrophic lateral sclerosis and head injuries from sports, military activity or car/truck accidents.

According to Dr. Van Dyke’s research, “the government of the U.S. spends three trillion dollars every year on disease treatment. Eighty-five percent of those total dollars are spent on poorly treated chronic diseases. Dr. Van Dyke has recognized that many chronic diseases like cancer, arthritis, diabetes and heart diseases etc. are caused by excessive peoxynitrite and/or its derivatives.” In looking to the future, Dr. Van Dyke hopes to continue to invent solutions for cellular luminescence and to measure the activity of the human immune system. His working philosophy is as follows: “Ben Franklin said it best when he stated, ‘An ounce of prevention is worth more than a pound of cure.’” For more information, visit www.medicine.hsc.wvu.edu.